CI

At a glance

ClinicalIndex Comparison Record
N/AActive· 60 enrolled
Drug / intervention
LLM SIC Summary Emailother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07147023
NCT07147023N/AActive

Better Real-time Information on Documentation of Goals of Care for Engagement in Serious Illness Communication

Dana-Farber Cancer Institute·interventional·Posted Aug 28, 2025·Updated Apr 28, 2026

In Brief

A clinical study evaluating LLM SIC Summary Email for Advanced Cancer and 2 related conditions. Active but no longer recruiting, targeting 60 participants across 2 sites.

Detailed Summary

The goal of this study is to test the accuracy of Large Language Model-generated serious illness communication (SIC) summaries, the feasibility of delivering the SIC summaries, and to collect perspectives on the SIC summaries from clinicians and participants with cancer. Large Language Models (LLMs) are artificial intelligence programs that can perform various natural language processing tasks.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/AActive
2026
First PostedAug 28, 2025
Enrollment StartSep 15, 2025
Primary CompletionApr 15, 2026
Study CompletionOct 31, 2026
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 10 months ago

Interventions

LLM SIC Summary Emailother

A Large Language Model-based platform is integrated with the Health Vision Platform, a HIPAA-compliant, electronic health record data management system. Real-time summaries of prior SIC with be sent to clinicians caring for participants in the intervention arm. An email will be sent to the inpatient attending and responding clinician encouraging the team to review the SIC summary, discuss care preferences with the patient and ensure care is aligned with preferences and goals. If no SIC documentation is found, the email will instead encourage the outpatient oncologist to share information regarding undocumented SICs that may have occurred, as well as prompt inpatient and outpatient teams to engage the patient in SIC. For patients with no SIC documentation who are still admitted 72 hours later, the RA will send an additional email prompting SIC or asking the clinician to indicate that an SIC is not appropriate. Patients will also receive standard of care.