CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 312 enrolled
Drug / intervention
Not specified
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07163988
NCT07163988N/ACompleted

High-Sensitivity Cardiac Troponin I as a Diagnostic Marker for AMI Clinical Stage Classification in Acute Myocardial Infarction: A Retrospective Multicenter Study

Rohan Dharmakumar·observational·Posted Sep 9, 2025·Updated May 20, 2026

In Brief

An observational study for Acute Myocardial Infarction (AMI). Completed, enrolled 312 participants across 1 site.

Detailed Summary

TROP-MI-STAGE is a multicenter retrospective diagnostic study designed to evaluate the role of high-sensitivity cardiac troponin I (hs-cTnI) in the diagnosis and clinical stage classification of acute myocardial infarction as defined by the stages of myocardial injury in CCS-AMI classification. The study retrospectively analyzes biomarker data from patients diagnosed with AMI across multiple institutions, focusing on whether hs-cTnI levels-measured at specific time points-can reliably identify and stratify patients into AMI clinical stages (Stage 1 to Stage 4). It aims to correlate hs-cTnI kinetics and peak levels with clinical stage, presentation patterns, and outcomes. This trial seeks to offer a biomarker-based alternative to imaging-heavy staging, potentially streamlining early diagnosis and therapeutic triage for AMI patients in varied clinical settings.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsIndiana University

Timeline

N/ACompletedFinished
2023202420252026
First PostedSep 9, 2025
Enrollment StartJan 10, 2023
Primary CompletionAug 31, 2025
Study CompletionSep 30, 2025
TodayJul 2, 2026
Enrollment to primary: 2.6 yearsPosted 10 months ago