At a glance
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Evaluation of Angiopoietin-like Protein 4 Levels in Patients With Endometriosis
In Brief
An observational study evaluating Angiopoietin-like protein-4 (ANGPTL4) Peritoneal Fluid Level, Cancer Antigen 125 (CA-125) Serum Level, and 1 other intervention for Endometriosis and 2 related conditions. Completed, enrolled 80 participants across 1 site.
Detailed Summary
Endometriosis is a chronic inflammatory disease associated with pelvic pain, dyspareunia, and impaired ovarian reserve. Cancer antigen-125 (CA-125) is widely studied but limited by low specificity, while angiopoietin-like protein-4 (ANGPTL4) has emerged as a potential biomarker due to its role in angiogenesis and inflammation. In the current study it was aimed to investigate serum and peritoneal fluid ANGPTL4 levels in women with endometriosis compared to healthy controls, and to evaluate their associations with clinical symptoms, serum CA-125, and anti-Müllerian hormone levels.
Study Details
Timeline
Interventions
Measurement of peritoneal fluid levels of Angiopoietin-like protein-4 (ANGPTL4) level by ELISA method.
Measurement of venous blood serum level of CA-125 level by ELISA method.
Measurement of venous blood serum level of Angiopoietin-like protein-4 (ANGPTL4) Level level by ELISA method.