CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 43 enrolled / 43 target
Drug / intervention
Self-swabbing of surgical woundprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07200401
NCT07200401N/ACompletedOn Track (7.4/mo)

A Feasibility Study to Explore the Safety, Acceptability and Potential Cost Effectiveness of Self-swabbing at Home to Obtain Usable Surgical Wound Culture Swabs

Guy's and St Thomas' NHS Foundation Trust·interventional·Posted Oct 1, 2025·Updated Jun 10, 2026

In Brief

A clinical study evaluating Self-swabbing of surgical wound for Cardiac Surgery and 4 related conditions. Completed, enrolled 43 participants across 2 sites.

Detailed Summary

The goal of this observational feasibility study is to learn if patients can safely, acceptably, and effectively collect their own wound swabs at home to detect clinically significant organisms in adults aged 18 and over who have had cardiac surgery via median sternotomy (central chest wound). Participants will be recruited from two sites: Harefield Hospital (Guy's and St Thomas' NHS Foundation Trust, London) and the Royal Sussex County Hospital (University Hospitals Sussex, Brighton). The main questions it aims to answer are: * Can home-based patient self-swabbing of surgical wounds provide swabs of sufficient quality for microbiological testing? * Is self-swabbing at home safe and acceptable to patients following cardiac surgery? * Could this approach be a cost-effective way to monitor for surgical wound infections? Participants will: * Receive a co-designed self-swabbing instruction pack, created in collaboration with a patient and public working group and clinical experts. * Be observed via Microsoft Teams by a research practitioner while self-swabbing (or having their carer do so) to assess usability and adherence to instructions. * Participate in a brief interview to share their experiences and feedback on the instructions and swabbing process. * Send completed swabs to the hospital laboratory for analysis to determine the usability and timeliness of the samples.

Study Details

Timeline

N/ACompletedFinished
2026
First PostedOct 1, 2025
Enrollment StartJan 6, 2026
Primary CompletionJun 2, 2026
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 9 months ago

Arms & Interventions

Self-Swabbing Groupexperimental

≥18 years old with median sternotomies (central wounds) after cardiac surgery will be drawn from two hospital sites

Procedure: Self-swabbing of surgical wound

Interventions

Self-swabbing of surgical woundprocedure

Participants will perform self-swabbing of their surgical wound under observation by a research practitioner via secure video call.