CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 80 enrolled
Drug / intervention
Papilla-preserving incision (Control) +2 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07204353
NCT07204353N/ACompleted

A Novel Surgical Procedure for Peri-implant Papilla Reconstruction in the Aesthetic Region: Modified Labial Pedicle Papilla Flap Technique With De-epithelialized Gingival Graft

Cuneyt Asim Aral·interventional·Posted Oct 2, 2025·Updated Oct 2, 2025

In Brief

A clinical study evaluating Papilla-preserving incision (Control), Modified Labial Pedicle Papilla Flap (mLPPF), and 1 other intervention for Peri-Implant Papilla Deficiency. Completed, enrolled 80 participants across 1 site.

Detailed Summary

This randomized controlled clinical trial aims to evaluate the effectiveness of two surgical techniques for peri-implant papilla reconstruction in single-tooth implants in the maxillary anterior and premolar regions. A total of 80 cases with papilla deficiency were allocated into three groups: papilla-preserving incisions only (Control), modified labial pedicle papilla flap (mLPPF), and mLPPF combined with a de-epithelialized gingival graft (mLPPF+dGG). Clinical outcomes including papilla fill (Jemt scores), papilla height, and crestal mucosa thickness were assessed at baseline, immediately after surgery, two weeks postoperatively, and six months after final restoration. The primary goal is to determine whether combining connective tissue grafting with flap surgery provides superior and more stable papilla reconstruction compared with papilla preserving flap-only approaches.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesTurkey (Türkiye)
Collaborators--

Timeline

N/ACompletedFinished
202120222023202420252026
First PostedOct 2, 2025
Enrollment StartFeb 1, 2021
Primary CompletionMay 25, 2024
Study CompletionJun 23, 2025
TodayJul 2, 2026
Enrollment to primary: 3.3 yearsPosted 9 months ago

Interventions

Papilla-preserving incision (Control)procedure

Standard papilla-preserving incision without additional flap modification or connective tissue grafting. This group serves as the control, receiving only routine surgical access for implant site management.

Modified Labial Pedicle Papilla Flap (mLPPF)procedure

Surgical reconstruction of the peri-implant papilla using the modified labial pedicle papilla flap technique. The flap is mobilized and sutured without adjunctive grafting procedures.

Modified Labial Pedicle Papilla Flap with De-epithelialized Gingival Graft (mLPPF+dGG)procedure

Surgical reconstruction of the peri-implant papilla combining the modified labial pedicle papilla flap with placement of a de-epithelialized gingival graft (dGG) at the papillary region to enhance soft tissue volume and stability.