At a glance
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Effects of Omega-3 Fatty Acid Supplementation on Muscle Damage and Oxylipin Production Induced by Eccentric Exercise in Young Men
In Brief
A clinical study evaluating Placebo and Omega for Damage Muscle. Completed, enrolled 30 participants across 1 site.
Detailed Summary
In recent decades, omega-3 eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been proposed as potential therapeutic agents for minimizing muscle damage induced by eccentric exercise, especially when supplementation is long-term (\> 6 weeks) and at high doses (\> 1 g/d). However, no study has analyzed whether these effects are mediated by an increase in oxylipins (metabolites derived from EPA and DHA), which play an essential role in the muscle regeneration process. The objective of the present study is to determine the effect of eight weeks of high-dose omega-3 fatty acid supplementation on blood oxylipin levels and their association with muscle function and markers of muscle damage after high-intensity eccentric exercise in young men.
Study Details
Timeline
Interventions
The participants will be supplemented with 5 capsules per day of a placebo-filled gelatin capsule for 8 weeks.
The participants will be supplemented with 5 capsules per day of Omega UP (Newscience, Chile), equivalent to 2.5 g/d of DHA and 0.5 g/d of EPA for 8 weeks