CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 15 enrolled
Drug / intervention
M6229 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07285603
NCT07285603Phase 1Completed

A Randomized, Single-blind, Placebo-controlled Study to Assess the Safety, Tolerability, and Pharmacokinetics of M6229 Administered as a 120-hour Continuous Infusion at Three Sequential Dose Levels Versus Placebo in Healthy Subjects

Matisse Pharmaceuticals·interventional·Posted Dec 16, 2025·Updated Dec 16, 2025

In Brief

A Phase 1 clinical trial evaluating M6229 and Placebo for Healthy Subjects. Completed, enrolled 15 participants across 1 site.

Detailed Summary

This is a Phase I, single-center, randomized, single-blind, placebo-controlled study in healthy subjects assessing the safety, tolerability and pharmacokinetic profile of three different dose levels of M6229 when administered continuously for 120 hours.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesGermany
Collaborators--

Timeline

Phase 1CompletedFinished
20252026
First PostedDec 16, 2025
Enrollment StartNov 21, 2024
Primary CompletionJun 18, 2025
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 7 months ago

Interventions

M6229drug

Continuous 120-hour intravenous infusion of M6229

Placebodrug

Continuous 120-hour intravenous infusion of placebo (saline)