At a glance
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Clinical Evaluation of Cold Plasma Surface Activation Using Different Plasma Systems on Early Implant Stability: A Randomized Controlled Within-Patient Trial
In Brief
A clinical study evaluating Dental implant placement, Dental implant placement and vacuum plasma application, and 2 other interventions for Cold Atmospheric Plasma and Dental Implants. Completed, enrolled 11 participants across 1 site.
Detailed Summary
Cold plasma-mediated implant surface activation may reverse the biological aging of titanium by enhancing hydrophilicity and cellular response. The aim of this study was to clinically compare the effects of three different cold plasma systems on the stability of dental implants. In this prospective randomized controlled within-patient trial, a total of 44 implants were placed in 11 patients. In each patient, four implants were randomly allocated to one of the following groups: control, vacuum plasma, argon jet plasma, and cold atmospheric plasma. All implants were placed using a single-stage protocol with a minimum insertion torque of 45 Ncm. Implant stability was assessed using resonance frequency analysis (ISQ values) immediately after placement and at 2, 4, and 8 weeks.
Study Details
Timeline
Interventions
The dental implant was placed without any plasma application.
The dental implant was placed with non-thermal low-pressure cold plasma application
The dental implant was placed with argon jet plasma application
The dental implant was placed with cold atmospheric plasma application