At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
The Protective Role of High-intensity Interval Exercise Compared With Continuous Moderate Exercise on Glycemia Decrease is More Relevant in Postabsorptive vs. Postprandial State in Adults With Type 1 Diabetes
In Brief
A clinical study evaluating High-intensity interval exercise performed in postprandial phase, High-intensity interval exercise performed in postabsorptive phase, and 2 other interventions for Diabetes Mellitus, Type 1. Completed, enrolled 21 participants across 1 site.
Detailed Summary
This randomized crossover trial examined whether exercise modality (high-intensity interval exercise vs. moderate-intensity continuous exercise) and timing relative to meals (postprandial vs. postabsorptive) influence glycemic responses in physically active adults with type 1 diabetes. Participants completed four cycling sessions matched for total mechanical load, and glucose levels were monitored during exercise and for 24 hours afterward while accounting for dietary intake and insulin administration. The study hypothesized that glycemic responses differ according to both exercise type and prandial state.
Study Details
Timeline
Interventions
Exercises were performed on a cycle ergometer (Excalibur Sport, Lode B.V.). Exercise began with a 3-min warm-up at 20% of maximum aerobic power (MAP) and ended with a 2-min active recovery at 20% of MAP. The high-intensity interval exercise protocol consisted of ten 1-min intervals at 100% of MAP, each interspersed with 1-min of passive recovery. For the postprandial state, exercise began 1.5 hours after the start of lunch and the corresponding meal-related bolus/rapid-acting insulin (i.e., in the early afternoon).
Exercises were performed on a cycle ergometer (Excalibur Sport, Lode B.V.). Exercise began with a 3-min warm-up at 20% of maximum aerobic power (MAP) and ended with a 2-min active recovery at 20% of MAP. The high-intensity interval exercise protocol consisted of ten 1-min intervals at 100% of MAP, each interspersed with 1-min of passive recovery. For the postabsorptive state, exercise began 5 hours after the start of lunch (i.e., in the late afternoon).
Exercises were performed on a cycle ergometer (Excalibur Sport, Lode B.V.). Exercise began with a 3-min warm-up at 20% of maximum aerobic power (MAP) and ended with a 2-min active recovery at 20% of MAP. The moderate-intensity continuous exercise protocol consisted of continuous exercise at 50% of MAP for 20 minutes. For the postprandial state, exercise began 1.5 hours after the start of lunch and the corresponding meal-related bolus/rapid-acting insulin (i.e., in the early afternoon).
Exercises were performed on a cycle ergometer (Excalibur Sport, Lode B.V.). Exercise began with a 3-min warm-up at 20% of MAP and ended with a 2-min active recovery at 20% of maximum aerobic power (MAP). The CONT protocol consisted of continuous exercise at 50% of MAP for 20 minutes. For the postabsorptive state, exercise began 5 hours after the start of lunch (i.e., in the late afternoon).