CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 200 enrolled
Drug / intervention
Lemongrass Inhaler +2 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07366294
NCT07366294N/ACompleted

Effects of Lemongrass (Cymbopogon Citratus) on Nicotine Dependence, Cotinine Levels, and Related Biomarkers in Adult Smokers

Titin Andri Wihastuti·interventional·Posted Jan 26, 2026·Updated Jan 26, 2026

In Brief

A clinical study evaluating Lemongrass Inhaler, Lemongrass Liquid Vapor, and 1 other intervention for Nicotine Dependence and 4 related conditions. Completed, enrolled 200 participants across 1 site.

Detailed Summary

The goal of this clinical trial is to learn whether lemongrass (Cymbopogon citratus) inhaler and liquid vapor interventions affect nicotine dependence and related biological and behavioral outcomes in adult smokers. The study will also evaluate changes in blood biomarkers, psychological well-being, and lifestyle-related measures. The main questions it aims to answer are: * Do lemongrass inhalers and/or liquid vapor reduce nicotine dependence and cotinine levels in adult smokers? * How do these interventions affect blood lipid profile and biomarkers of inflammation, oxidative stress, endothelial function, and stress response, including interleukin-6 (IL-6), malondialdehyde (MDA), superoxide dismutase (SOD), nitric oxide (NO), cortisol, and nicotinic acetylcholine receptors (nAChRs)? * Do lemongrass inhaler and liquid vapor influence appetite, physical fitness, sleep quality, and psychological status measured using the Depression, Anxiety, and Stress Scale (DASS)? Researchers will compare participants receiving lemongrass inhaler, lemongrass liquid vapor, or a combination of both to a control group receiving no intervention to evaluate the effects of the interventions. Participants will: * Receive a lemongrass inhaler, lemongrass liquid vapor, a combination of both, or no intervention according to group assignment * Continue their usual daily activities during the study period * Provide blood samples and complete questionnaires to assess biochemical markers, nicotine dependence, appetite, fitness level, sleep quality, and psychological status

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesIndonesia

Timeline

N/ACompletedFinished
20252026
First PostedJan 26, 2026
Enrollment StartOct 7, 2024
Primary CompletionNov 7, 2024
Study CompletionNov 10, 2024
TodayJul 2, 2026
Enrollment to primary: 1 monthPosted 5 months ago

Interventions

Lemongrass Inhalerother

Participants receive a lemongrass (Cymbopogon citratus) inhaler administered by inhalation according to the study protocol.

Lemongrass Liquid Vaporother

Participants receive lemongrass (Cymbopogon citratus) liquid vapor administered via vaporization according to the study protocol.

Lemongrass Inhaler and Liquid Vaporother

Participants receive a combination of lemongrass (Cymbopogon citratus) inhaler and liquid vapor administered concurrently according to the study protocol.