CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 16 enrolled
Drug / intervention
β-tricalcium phosphate Injectable Bone Graft +2 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07368114
NCT07368114Phase 2Completed

Validity of Ozonated Olive Oil Gel Versus Injectable Bone Graft on Osseointegration of Immediate Dental Implants

Suez Canal University·interventional·Posted Jan 26, 2026·Updated Jan 26, 2026

In Brief

A Phase 2 clinical trial evaluating Immediate implant placement, β-tricalcium phosphate Injectable Bone Graft, and 1 other intervention for Dental and 3 related conditions. Completed, enrolled 16 participants across 1 site.

Detailed Summary

Many of studies have been performed to improve osseointegration and bone density around implants by modifying the implant by adding bone graft or substitute material that increase success of implant. The aim of this study is to evaluate clinically and radiographically the efficacy of injectable bone graft versus ozonated olive oil gel to promote bone formation and improve outcomes in immediate implant cases. 16 immediate implants will be placed in mandibular premolar region the study will be devided equally and randomlly into two groups , Group 1: it will be 8 immediate implants represent the control group were the implants will be placed with injectable bone graft , Group 2: will be 8 immediate implant represent the study group were the implants will be placed with ozonated olive oil gel be used as a graft material . The implant stability will be assessed clinically using Ostell , and the bone density will be assed radiographically .

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesEgypt
Collaborators--

Timeline

Phase 2CompletedFinished
202420252026
First PostedJan 26, 2026
Enrollment StartDec 10, 2023
Primary CompletionMay 10, 2025
Study CompletionSep 10, 2025
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 5 months ago

Interventions

Immediate implant placementprocedure

Placement of a dental implant immediately after tooth extraction in the mandibular premolar region following standard surgical protocol.

β-tricalcium phosphate Injectable Bone Graftbiological

Immediate implant placement in the mandibular premolar region with application of injectable bone graft material to the peri-implant defect.

Ozonated olive oil gelbiological

Immediate implant placement in the mandibular premolar region with application of ozonated olive oil gel to the peri-implant defect.