CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 45 enrolled
Drug / intervention
Experimental - Self-Guided CBT Mobile Appbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07391943
NCT07391943N/ACompleted

Efficacy of a Self-Guided Cognitive Behavioral Therapy Protocol Via Mobile Application in Patients With Treatment-Resistant Panic Disorder: An Open-Label Trial

Universidade Federal do Rio de Janeiro·observational·Posted Feb 6, 2026·Updated Feb 6, 2026

In Brief

An observational study evaluating Experimental - Self-Guided CBT Mobile App for Panic Disorder. Completed, enrolled 45 participants across 1 site.

Detailed Summary

Treatment-resistant panic disorder (TRPD) is characterized by persistent panic symptoms despite adequate pharmacological and/or psychotherapeutic treatment. This open-label study is designed to evaluate a self-guided cognitive behavioral therapy (CBT) protocol delivered via a mobile application for adults with TRPD. The intervention consists of eight weekly sessions covering psychoeducation, panic cycle interruption, cognitive restructuring, relaxation techniques, assertiveness training, behavioral strategies, and life reorganization. An avatar is incorporated to enhance engagement and simulate therapeutic presence. Participants continue their usual psychiatric follow-up and pharmacological treatment throughout the study. Outcomes are assessed at baseline and after completion of the intervention using validated measures of panic severity, anxiety, depression, mindfulness, coping strategies, quality of life, and affect.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsPanic Disorder
CountriesBrazil
Collaborators--

Timeline

N/ACompletedFinished
20252026
First PostedFeb 6, 2026
Enrollment StartNov 1, 2024
Primary CompletionMay 30, 2025
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 5 months ago

Interventions

Experimental - Self-Guided CBT Mobile Appbehavioral

Eight-session manualized CBT protocol delivered via mobile app, including psychoeducation, cognitive restructuring, relaxation, behavioral activation, assertiveness, and life reorganization, with avatar interface to enhance engagement.