CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 116 enrolled / 116 target
Drug / intervention
Herbal Formulation +2 moredrug
Likely dose
Metformin 750 mg and herbal formulation 500 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07399535
NCT07399535Phase 1CompletedOn Track (7.1/mo)Completion was 4mo ago
CompareCT.gov

Clinical Investigation of Herbal Formulation and Its Efficacy in Polycystic Ovarian Syndrome

Jinnah Postgraduate Medical Centre·interventional·Posted Feb 10, 2026·Updated Jun 23, 2026

In Brief

A Phase 1 clinical trial evaluating Herbal Formulation, Metformin XR, and 1 other intervention for Polycystic Ovarian Syndrome (PCOS) and 3 related conditions. Completed, enrolled 116 participants across 1 site.

Detailed Summary

Polycystic Ovarian Syndrome (PCO) is a metabolic disorder that afflicts the women of childbearing age. An approximate of 5-10% women are the victim of this disorder. PCOS is a leading cause of infertility in females these days and is characterized by Hyperandrogenism, Chronic Anovulation, Impaired fertility, obesity, Hirsutism, Acne, Obesity, Metabolic disturbances (dyslipidemias, Hyperinsulinemia, insulin resistance, and type- 2 diabetes), and Endometrial Hyperplasia. This study will test a combination of herbal medications (Melats P) in women with PCOS to determine which works best to overcome infertility.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPolycystic Ovarian Syndrome (PCOS), Herbal Medicine, Infertility, Metabolic Disorder
CountriesPakistan
Collaborators--

Timeline

Phase 1CompletedFinished
2026
First PostedFeb 10, 2026
Enrollment StartFeb 22, 2025
Primary CompletionFeb 22, 2026
Study CompletionMar 1, 2026
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 5 months ago

Arms & Interventions

Herbal formulation treated groupexperimental

Herbal formulation 500 mg twice daily for 4 months in PCOS patients

Drug: Herbal Formulation
Metformin XR treated groupactive_comparator

Metformin XR 750 mg twice daily for 4 months in PCOS patients

Drug: Metformin XR
Adjunct Groupexperimental

Herbal formulation 500 mg and Metformin XR 750 mg twice daily for 4 months in PCOS patient

Drug: Metformin 750 mg and herbal formulation 500 mg

Interventions

Herbal Formulationdrug

Herbal Formulation 500mg twice daily for 4 months in PCOS patients

Metformin XRdrug

Metformin XR 750mg twice daily for 4 months in PCOS patients

Metformin 750 mg and herbal formulation 500 mgdrug

Herbal formulation and Metformin twice daily for 4 months in PCOS patients