CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 36 enrolled
Drug / intervention
traditional rehabilitation protocol +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07406763
NCT07406763N/ACompleted

Effect of Adding Blood Flow Restriction to Traditional Program After Anterior Cruciate Ligament Reconstruction: A Double-Blinded Randomized Controlled Trial

Ahmed Mohamed Mahmoud Abdelaziz Khalil·interventional·Posted Feb 12, 2026·Updated Feb 12, 2026

In Brief

A clinical study evaluating traditional rehabilitation protocol and Blood Flow Restriction for Blood Flow Restriction Therapy and Anterior Cruciate Ligament (ACL). Completed, enrolled 36 participants across 2 sites.

Detailed Summary

The goal of this clinical trial is to learn whether adding blood flow restriction (BFR) training to a traditional rehabilitation protocol (TRP) can improve muscle strength, knee proprioception, range of motion, pain, and lower limb function after anterior cruciate ligament reconstruction (ACLR). This study is conducted in male and female adults aged 18-35 years who underwent ACLR using a semitendinosus tendon autograft. The main questions it aims to answer are: Does adding BFR to a traditional rehabilitation protocol improve quadriceps and hamstring muscle strength after ACLR? Does adding BFR improve knee joint proprioception, range of motion, pain, and lower limb function after ACLR? Researchers compared a traditional rehabilitation protocol alone (control group) with the same protocol combined with blood flow restriction training (BFR group) to see if BFR provides superior improvements in postoperative outcomes. Participants was: randomly assigned to either a traditional rehabilitation group or a BFR-assisted rehabilitation group Perform supervised rehabilitation exercises from the 2nd to the 12th postoperative week Undergo assessments of muscle strength, knee proprioception, range of motion, pain, and function Be evaluated 1 week before surgery and at 1.5 and 3 months after ACL reconstruction

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesEgypt
CollaboratorsCairo University

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedFeb 12, 2026
Enrollment StartFeb 1, 2020
Primary CompletionFeb 1, 2021
Study CompletionFeb 1, 2022
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 5 months ago

Interventions

traditional rehabilitation protocolother

The traditional rehabilitation protocol includes progressive therapeutic exercises aimed at restoring: Quadriceps and hamstring muscle strength Knee joint range of motion Neuromuscular control and functional performance

Blood Flow Restrictiondevice

Blood flow restriction was applied to the proximal thigh of the operated limb using a specially designed sphygmomanometer cuff capable of partially restricting arterial inflow and venous outflow during exercise. BFR was used during low-load resistance exercises targeting the quadriceps and hamstring muscles, in accordance with postoperative safety guidelines.