CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 66 enrolled
Drug / intervention
Bupivacaine-Magnesium Sulphate +2 morecombination
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07418671
NCT07418671Phase 2Completed
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Ultrasound Guided Lumbar Erector Spinae Block Using Bupivacaine - Magnesium Sulphate Versus Bupivacaine - Dexamethasone in Total Hip Replacement Surgery

Ain Shams University·interventional·Posted Feb 18, 2026·Updated Feb 18, 2026

In Brief

A Phase 2 clinical trial evaluating Bupivacaine-Magnesium Sulphate, Bupivacaine-Dexamethasone, and 1 other intervention for Post-operative Pain and 2 related conditions. Completed, enrolled 66 participants across 1 site.

Detailed Summary

The current study was done to evaluate the effect of adding dexamethasone and magnesium sulfate to bupivacaine as adjuvants in an ultrasound-guided erector spinae block for patients undergoing total hip arthroplasty (THA), and to assess their impact on the timing of the first request for analgesia and on overall postoperative analgesic requirements.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPost-operative Pain, Total Hip Arthroplasty (THA), Erector Spinae Plane Block
CountriesEgypt
Collaborators--

Timeline

Phase 2CompletedFinished
2026
First PostedFeb 18, 2026
Enrollment StartMay 1, 2025
Primary CompletionNov 1, 2025
Study CompletionNov 25, 2025
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 4 months ago

Interventions

Bupivacaine-Magnesium Sulphatecombination

Bupivacaine plus Magnesium Sulphate (MgSO4) as adjuvant

Bupivacaine-Dexamethasonecombination

Bupivacaine plus Dexamethasone as adjuvant

Bupivacaine-Salinecombination

Bupivacaine plus Saline as control