CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 40 enrolled
Drug / intervention
non-surgical periodontal treatment +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07450573
NCT07450573N/ACompleted

Impact of Periodontal Therapy on Function and Quality of Life in Stage III Periodontitis

Ankara Medipol University·interventional·Posted Mar 4, 2026·Updated Mar 4, 2026

In Brief

A clinical study evaluating non-surgical periodontal treatment and surgical periodontal treatment for Periodontitis. Completed, enrolled 40 participants across 1 site.

Detailed Summary

Stage III, Grade B periodontitis is a severe form of gum disease that damages the tissues and bone supporting the teeth. It can cause loose teeth, difficulty chewing, and reduced quality of life. Although periodontal (gum) treatment is known to improve gum health, less is known about how it affects chewing ability and how patients feel about their oral health after treatment. This study looked at how comprehensive periodontal treatment affects gum health, chewing function, and oral health-related quality of life. Twenty patients with Stage III, Grade B periodontitis and twenty individuals with healthy gums participated. Patients with periodontitis received non-surgical treatment (deep cleaning and root surface debridement) followed, when needed, by surgical periodontal therapy. Researchers measured gum health (including probing depth and bleeding), tooth mobility, chewing performance, and patient-reported quality of life. Chewing performance was tested using a standardized chewing test with silicone material. Quality of life was assessed using a validated questionnaire (OHIP-14), which measures how oral health affects daily life, comfort, and well-being. Assessments were performed before treatment, after non-surgical therapy, and after surgical treatment. At the start of the study, patients with periodontitis had worse gum health, poorer chewing ability, and lower oral health-related quality of life compared to healthy individuals. After treatment, gum inflammation and tooth mobility significantly improved. Chewing ability also improved after therapy, especially after surgical treatment. Patients reported better quality of life, with fewer symptoms and less discomfort. The study also found that better chewing performance was strongly associated with better quality of life. This suggests that improving function is closely linked to how patients feel about their oral health. Overall, comprehensive periodontal therapy not only improves clinical gum health but also enhances chewing efficiency and patient well-being. These findings highlight the functional and quality-of-life benefits of periodontal rehabilitation in patients with advanced gum disease.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPeriodontitis
CountriesTurkey (Türkiye)
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedMar 4, 2026
Enrollment StartDec 1, 2019
Primary CompletionJul 1, 2021
Study CompletionJul 5, 2021
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 4 months ago

Interventions

non-surgical periodontal treatmentprocedure

non-surgical periodontal treatment

surgical periodontal treatmentprocedure

Periodontitis patients underwent surgical periodontal treatments.