At a glance
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Effects of Aerobic and Resistance Exercises on Cardiovascular Biomarkers in Sedentary Females: A Randomized Controlled Trial
In Brief
A clinical study evaluating Aerobic Exercise Training and Resistance Exercise Training for Sedentary Lifestyle and Cardiometabolic Risk. Completed, enrolled 45 participants across 1 site.
Detailed Summary
This randomized controlled trial investigated the effects of aerobic and resistance exercise on cardiovascular and inflammatory biomarkers in sedentary young women. Forty-five healthy sedentary females aged 18 to 25 years were randomly assigned to aerobic exercise, resistance exercise, or control groups. The exercise groups trained three times per week for 8 weeks under supervision, while the control group maintained a sedentary lifestyle. Blood samples and physiological measurements were obtained at baseline and after the intervention. The primary aim was to evaluate changes in circulating natriuretic peptides and inflammatory biomarkers, including NT-proBNP, BNP, soluble ST2, and Galectin-3. Secondary outcomes included lipid profile, glucose and insulin levels, blood pressure, and aerobic fitness. The study examined whether different exercise modalities induce beneficial cardiometabolic adaptations in previously sedentary young women.
Study Details
Timeline
Interventions
Supervised treadmill-based moderate-intensity walking and jogging at 60-75% of heart rate reserve, 60 minutes per session including warm-up and cool-down, three sessions per week for 8 weeks.
Supervised whole-body resistance training including major muscle group exercises, performed as 3 sets of 8-10 repetitions at approximately 70-80% of one-repetition maximum, three sessions per week for 8 weeks.