At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effectiveness and Safety of Povidone-Iodine Irrigation for Postoperative Management of Chronic Rhinosinusitis
In Brief
A clinical study evaluating Normal Saline Nasal Irrigation, Acetylcysteine (Mucomyst) Nasal Irrigation, and 1 other intervention for Chronic Rhinosinusitis. Completed, enrolled 48 participants across 1 site.
Detailed Summary
This prospective randomized controlled trial evaluates the effectiveness and safety of different nasal irrigation solutions for postoperative care after endoscopic sinus surgery in patients with chronic rhinosinusitis. Patients undergoing endoscopic sinus surgery will be randomly assigned to receive nasal irrigation with normal saline, mucomyst, or diluted povidone-iodine solution for three months after surgery. Clinical outcomes, symptom scores, endoscopic findings, and potential ototoxic effects will be evaluated to compare the effectiveness and safety of these irrigation methods.
Study Details
Timeline
Interventions
Postoperative nasal irrigation using normal saline solution for 3 months after endoscopic sinus surgery.
Postoperative nasal irrigation using acetylcysteine solution for 3 months after endoscopic sinus surgery.
Postoperative nasal irrigation using diluted 0.5% povidone-iodine solution for 3 months after endoscopic sinus surgery.