CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 84 enrolled
Drug / intervention
1 drop of a 0.8% tropicamide + 5% phenylephrine combination +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07495670
NCT07495670N/ACompleted
CompareCT.gov

Comparison of Mydriatic Effects Between 4 Regimens of a Tropicamide-Phenylephrine Combination in Diabetic Patients

Burapha University·interventional·Posted Mar 27, 2026·Updated Mar 27, 2026

In Brief

A clinical study evaluating 1 drop of a 0.8% tropicamide + 5% phenylephrine combination, 1 drop of 0.5% tetracaine and 1 drop of a 0.8% tropicamide + 5% phenylephrine combination, and 2 other interventions for Diabetes (DM) and 2 related conditions. Completed, enrolled 84 participants across 1 site.

Detailed Summary

Pupil dilation is required for many eye conditions. Diabetic patients may need more dilating eye drops to have pupil size large enough for eye exams. This study compares 4 methods of eye drops for pupil dilation in diabetic patients scheduled for retinopathy screening. Possible side effects of the eye drops are monitored during the study.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDiabetes (DM), Retinopathy, Diabetic, Pupil Dilation
CountriesThailand
Collaborators--

Timeline

N/ACompletedFinished
20252026
First PostedMar 27, 2026
Enrollment StartNov 4, 2024
Primary CompletionJan 31, 2025
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 3 months ago

Interventions

1 drop of a 0.8% tropicamide + 5% phenylephrine combinationdrug

1 drop of a 0.8% tropicamide (muscarinic antagonist) + 5% phenylephrine (α1-adrenergic agonist) combination

1 drop of 0.5% tetracaine and 1 drop of a 0.8% tropicamide + 5% phenylephrine combinationdrug

1 drop of 0.5% tetracaine (anesthetics) and 1 drop of a 0.8% tropicamide (muscarinic antagonist) + 5% phenylephrine (α1-adrenergic agonist) combination

3 drops of a 0.8% tropicamide + 5% phenylephrine combinationdrug

3 drops of a 0.8% tropicamide (muscarinic antagonist) + 5% phenylephrine (α1-adrenergic agonist) combination

1 drop of 0.5% tetracaine and 3 drops of a 0.8% tropicamide + 5% phenylephrine combinationdrug

1 drop of 0.5% tetracaine (anesthetics) and 3 drops of a 0.8% tropicamide (muscarinic antagonist) + 5% phenylephrine (α1-adrenergic agonist) combination