CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 1,229 enrolled
Drug / intervention
Primary Healthcare-Integrated Service Delivery +1 moreother
Likely dose
Not stated in record
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Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07507461
NCT07507461N/ACompleted

Protocol for a Community Case Study on Integrating Schistosomiasis and Soil-Transmitted Helminthiasis Mass Drug Administration Into Primary Health Care in Western Kenya

Amref Health Africa·interventional·Posted Apr 2, 2026·Updated Apr 2, 2026

In Brief

A clinical study evaluating Primary Healthcare-Integrated Service Delivery and Standard Mass Drug Adminitsration service delivery for Soil Transmitted Helminth (STH) Infections and Schistosomiasis Infection. Completed, enrolled 1,229 participants across 1 site.

Detailed Summary

This study aims to determine whether distributing deworming drugs through routine healthcare services at the first point of contact in the health system is an effective way to prevent and treat worm infections in Western Kenya. This will be compared to the current campaign-based method that operates outside the health system. The main questions it aims to answer are: * Is the alternative method suitable and achievable in the targeted area? * What percentage of the population does this method cover? How does it compare with the current method? * How cost-effective is this alternative method? Researchers will compare outcomes in wards where the integrated method of drug administration is implemented (intervention arm) to wards where the standard campaign-based method is continued (control arm) to answer these questions. Participants from both arms of the study will: * Community members will respond to survey questions on their experience and access levels to deworming drugs. Some will also participate in Focus Group Discussions. * Health facility heads will be interviewed to assess the health facility and collect cost data. * Key stakeholders within the county administration will be engaged in key informant interviews. * Community Health Promoters will participate in Focus Group Discussions.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesKenya
Collaborators--

Timeline

N/ACompletedFinished
2026
First PostedApr 2, 2026
Enrollment StartMay 22, 2025
Primary CompletionOct 10, 2025
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 3 months ago

Interventions

Primary Healthcare-Integrated Service Deliveryother

* Service Delivery: Embedding Mass Drug Administration (MDA) into routine service delivery channels within PHC platforms, including health facilities and schools. * Health Workforce: Training PHC staff in STH/SCH case management, adverse event reporting, and integration. * Community Engagement: Through the use of the electronic Community Health Information System (eCHIS), Community Health Promoters (CHPs) support treatment delivery and conduct household and school-based follow-ups. * Sustainability: Transition from donor-dependent MDA campaigns to county-led, sustainably budgeted deworming services, fully embedded within routine PHC planning. * Integration of NTD indicators into national data systems such as DHIS2 and eCHIS.

Standard Mass Drug Adminitsration service deliveryother

Campaign-based MDA, which is primarily donor-funded, implemented through community drug distributors (CDDs), and conducted separately from routine health services. Control sites will be selected from among the 122 Non-Interruption of Transmission (Non-IoT) wards that follow this conventional model.