At a glance
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Comparative Effectiveness of Postoperative Hormonal Regimens After Ovarian Endometrioma Cystectomy: A Weighted Retrospective Cohort Study
In Brief
An observational study for Ovarian Endometrioma and Endometriosis. Completed, enrolled 1,121 participants across 1 site.
Signals
Detailed Summary
This retrospective cohort study evaluates the association between postoperative hormonal treatment and recurrence of ovarian endometriosis in women undergoing surgery for ovarian endometrioma. The study includes patients treated at a single center who initiated one postoperative hormonal regimen after surgery. The main objective is to compare the risk of recurrence among women receiving combined oral contraceptives, gonadotropin-releasing hormone agonists, dienogest, or dydrogesterone. Recurrence is assessed during follow-up based on postoperative clinical and ultrasound findings. The results may help clarify the comparative effectiveness of commonly used postoperative hormonal strategies for reducing recurrence after surgery for ovarian endometrioma.
Study Details
Timeline
Arms & Interventions
Participants who received combined oral contraceptives as postoperative hormonal therapy in routine clinical practice after surgery for ovarian endometrioma.
Participants who received gonadotropin-releasing hormone agonists as postoperative hormonal therapy in routine clinical practice after surgery for ovarian endometrioma.
Participants who received dienogest as postoperative hormonal therapy in routine clinical practice after surgery for ovarian endometrioma.
Participants who received dydrogesterone as postoperative hormonal therapy in routine clinical practice after surgery for ovarian endometrioma.