CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 38 enrolled
Drug / intervention
Er,Cr:YSGG laser +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07520266
NCT07520266N/ACompleted

Comparison of Diode and Er,Cr:YSGG Lasers in Gingival Depigmentation: a Split-mouth Randomized Trial

Can Tho University of Medicine and Pharmacy·interventional·Posted Apr 9, 2026·Updated Apr 14, 2026

In Brief

A clinical study evaluating Er,Cr:YSGG laser and Diode laser for Gingival Hyperpigmentation. Completed, enrolled 38 participants across 2 sites.

Detailed Summary

Gingival hyperpigmentation is a common physiological condition caused by excessive melanin deposition in oral mucosa, negatively affecting smile esthetics. Laser therapy has become an effective treatment option due to advantages such as minimal bleeding, reduced postoperative discomfort, and faster healing. This clinical study aims to evaluate clinical characteristics of gingival pigmentation and compare treatment outcomes between diode laser and Er,Cr:YSGG laser techniques. Outcomes include pigmentation reduction, postoperative pain, wound healing, bleeding, patient satisfaction, and recurrence rate.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesVietnam
Collaborators--

Timeline

N/ACompletedFinished
202420252026
First PostedApr 9, 2026
Enrollment StartMar 1, 2023
Primary CompletionMay 1, 2024
Study CompletionMay 1, 2025
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 3 months ago

Interventions

Er,Cr:YSGG laserdevice

The group Er,Cr:YSGG (2780 nm) has a wavelength of 2780 nm, a pulse duration of 140-150 microseconds, a power output of 2.5W, a steam content of 11%, and a water content of 30%.

Diode laserother

The Group Laser Diode (940 nm) has a wavelength of 940 to 10 nm, a pulse length of 15 microseconds, and a power output of 2.5 W. Activate the fiber laser head by touching the tip to the colored paper.