At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Comparison of Buccal Midazolam Versus Inter-muscular Midazolam in Control of Seizures
In Brief
A Phase 4 clinical trial evaluating Midazolam for Seizure Disorder Generalized Tonic Clonic. Completed, enrolled 90 participants across 1 site.
Signals
Detailed Summary
The goal of this clinical trial(Quasi Experimental) is to compare efficacy of oral midazolam over intra-muscular Midazolam in children suffering from seizures. The main question it aims to answer is: Does Buccal midazolam has a better efficacy as compared to intramuscular midazolam in children presenting with seizures? There will be two groups determined by randomisation and then one will be given buccal midazolam and other will will be administered IM Midazolam .The out come will be determined by the determining the cessation of seizures within 5 minutes duration achieved by administration of drug.
Study Details
Timeline
Arms & Interventions
In group A, children were given intramuscular midazolam in the thigh at 0.05 ml/kg (maximum 1.6 ml).
In group B, children were given buccal midazolam at 0.06 ml/kg (maximum 2 ml)
Interventions
In group A, children were given intramuscular midazolam in the thigh at 0.05 ml/kg (maximum 1.6 ml). In group B, children were given buccal midazolam at 0.06 ml/kg (maximum 2 ml).