CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 40 enrolled / 40 target
Drug / intervention
Isometric Exercise +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT07627152
NCT07627152N/ACompletedHigh Momentum (2.7/mo)Completion was 11mo ago

Effects of Isometric Exercise on Recovery Following Experimentally Induced Delayed Onset Muscle Soreness: A Randomized Controlled Trial

Istanbul Nisantasi University·interventional·Posted Jun 4, 2026·Updated Jun 16, 2026

In Brief

A clinical study evaluating Isometric Exercise and Sham Exercise for Delayed Onset Muscle Soreness (DOMS). Completed, enrolled 40 participants across 1 site.

Signals

Enrolling ahead of pace

Detailed Summary

The goal of this clinical trial is to learn whether isometric exercise can improve recovery following experimentally induced delayed onset muscle soreness (DOMS) in healthy young adults. The main questions it aims to answer are: * Does isometric exercise reduce pain associated with delayed onset muscle soreness? * Does isometric exercise improve pressure pain threshold, knee joint range of motion, muscle strength, and recovery following delayed onset muscle soreness? Researchers will compare participants performing an isometric exercise program with a control group receiving no intervention to determine whether isometric exercise improves recovery after experimentally induced DOMS. Participants will: * Undergo a standardized exercise protocol to induce delayed onset muscle soreness. * Be randomly assigned to either an isometric exercise group or a control group. * Complete assessments of pain intensity, pressure pain threshold, knee range of motion, muscle strength, and thigh circumference. * Be evaluated before exercise, immediately after exercise, and on Days 1, 3, and 5 following DOMS induction.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesTurkey (Türkiye)
Collaborators--

Timeline

N/ACompletedFinished
2026
First PostedJun 4, 2026
Enrollment StartApr 1, 2025
Primary CompletionJul 18, 2025
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 28 days ago

Arms & Interventions

Isometric Exercise Groupexperimental

Participants in this group underwent a standardized protocol to induce delayed onset muscle soreness (DOMS) and subsequently performed a structured quadriceps isometric exercise program during the recovery period.

Other: Isometric Exercise
Sham Exercise Groupsham_comparator

Participants performed a sham exercise protocol following experimentally induced delayed onset muscle soreness. The sham intervention was designed to mimic the attention and participation associated with the experimental intervention without providing the intended therapeutic effect.

Other: Sham Exercise

Interventions

Isometric Exerciseother

Participants performed a structured quadriceps isometric exercise program following experimentally induced delayed onset muscle soreness. The exercise protocol was applied according to the study protocol throughout the recovery period.

Sham Exerciseother

Participants performed a sham exercise protocol following experimentally induced delayed onset muscle soreness. The sham intervention was designed to mimic the attention and participation associated with the experimental intervention without providing the intended therapeutic effect.