At a glance
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Prospective Validation of the BBCMADE Nomogram for Predicting High-Risk Gastric Content in Patients Undergoing Elective Sedative Gastrointestinal Endoscopy
In Brief
An observational study evaluating BBCMADE Nomogram and Endoscopic Gastric Volume and pH Measurement for Gastric Content Aspiration Risk and 2 related conditions. Completed, enrolled 533 participants across 1 site.
Signals
Detailed Summary
This prospective observational study aims to validate the BBCMADE nomogram (Body Mass Index, Brain infarction, Cirrhosis, Male sex, Age, Diabetes, Esophageal reflux) for predicting high-risk gastric content in patients undergoing elective sedative gastrointestinal endoscopy in a Turkish population. Nomogram-predicted risk scores will be compared against the gold standard - endoscopically measured gastric volume and content. High-risk gastric content is defined as gastric volume ≥25 mL, pH \<2.5, or presence of solid content. The nomogram is a non-invasive, web-based, easily applicable screening tool that requires no additional training or equipment, and may contribute to safer anesthesia management by identifying high-risk patients prior to the procedure.
Study Details
Timeline
Arms & Interventions
Patients scheduled for elective sedative gastrointestinal endoscopy. Gastric volume and pH were measured endoscopically during the procedure. Patients were classified as high or low aspiration risk based on endoscopic measurements. The BBCMADE nomogram score was calculated for each patient and compared against the endoscopic findings to validate its predictive accuracy.
Interventions
The BBCMADE nomogram (Body Mass Index, Brain infarction, Cirrhosis, Male sex, Age, Diabetes, Esophageal reflux) is applied to predict high-risk gastric content prior to elective sedative gastrointestinal endoscopy. Nomogram scores are compared against the gold standard endoscopic measurement of gastric volume and pH to prospectively validate the model in a Turkish population.
Gold-standard assessment of gastric contents is performed during endoscopy. Gastric volume ≥25 mL, pH \<2.5, or the presence of solid content is defined as high risk for pulmonary aspiration.